Auramine (CAS 492-80-8)
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Auramine, a widely used fluorescent dye in scientific research, exhibits a yellow-green crystal structure and dissolves readily in water and ethanol. Also referred to as Basic Yellow 2, it belongs to the acridine family of dyes. In the realm of scientific research, hstology and pathology benefit from Auramine′s staining capabilities for tissues and cells. By employing fluorescence microscopy, Auramine enables the visualization of cellular and tissue structure and function. Auramine′s mode of action involves binding to nucleic acids, specifically DNA and RNA. When exposed to ultraviolet light, it exhibits fluorescence. Its high affinity for acid-fast bacteria arises from their cell walls′ abundant lipid content. When used in conjunction with a counterstain like rhodamine, fluorescence microscopy reveals acid-fast bacteria as bright yellow-green rods.
Auramine (CAS 492-80-8) References
- Auramine phenol staining of smears for screening acid fast bacilli in clinical specimens. | Kumar, VA. and Chandra, PS. 2008. J Commun Dis. 40: 47-52. PMID: 19127669
- Auramine-O as a fluorescence marker for the detection of amyloid fibrils. | Amdursky, N. and Huppert, D. 2012. J Phys Chem B. 116: 13389-95. PMID: 23088764
- UV-fixed-thick-blotch preparation improves sensitivity of auramine staining. | Cejudo-García, MA., et al. 2013. J Clin Microbiol. 51: 3400-2. PMID: 23863571
- Auramine-phenol vs. modified Kinyoun's acid-fast stains for detection of coccidia parasites. | Abou El-Naga, IF. and Gaafar, MR. 2014. Lab Med. 45: 65-73. PMID: 24719990
- Auramine O, an incense smoke ingredient, promotes lung cancer malignancy. | Tung, JC., et al. 2017. Environ Toxicol. 32: 2379-2391. PMID: 28722353
- Auramine-o (Synthetic Yellow Cow Dung Powder) Poisoning: Rare but Fatal. | Dhadke, S., et al. 2017. J Assoc Physicians India. 65: 18-20. PMID: 28792163
- Auramine-Rhodamine Stain-Detection of Mycobacteria in Ocular Fluid. | Bajgai, P., et al. 2017. Ophthalmol Retina. 1: 513. PMID: 31047444
- Auramine O in foods and spices determined by an UPLC-MS/MS method. | Tran-Lam, TT., et al. 2020. Food Addit Contam Part B Surveill. 13: 171-176. PMID: 32238061
- Auramine dyes induce toxic effects to aquatic organisms from different trophic levels: an application of predicted non-effect concentration (PNEC). | de Jesus Azevedo, CC., et al. 2021. Environ Sci Pollut Res Int. 28: 1866-1877. PMID: 32857307
- Machine-assisted interpretation of auramine stains substantially increases through-put and sensitivity of microscopic tuberculosis diagnosis. | Horvath, L., et al. 2020. Tuberculosis (Edinb). 125: 101993. PMID: 33010589
- Label free detection of auramine O by G-quadruplex-based fluorescent turn-on strategy. | Güner, D., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 267: 120532. PMID: 34776374
- DNA-Templated Modulation in the Photophysical Properties of a Fluorescent Molecular Rotor Auramine O by Varying the DNA Composition. | Pramanik, S., et al. 2022. J Phys Chem B. 126: 2658-2668. PMID: 35357836
- Behavior of Auramine O in the Aqueous Solution of Two Kolliphors and Their Mixture. | Szymczyk, K., et al. 2022. Molecules. 27: PMID: 36500588
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Auramine, 25 mg | sc-252393 | 25 mg | $168.00 |