AtosibanA peptide oxytocin receptor inhibitor

Atosiban (CAS 90779-69-4)

Atosiban | CAS 90779-69-4 is rated 5.0 out of 5 by 1.
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Synonym: 1-(3-Mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithineoxytocin
Application: A peptide oxytocin receptor inhibitor
CAS Number: 90779-69-4
Purity: ≥98%
Molecular Weight: 994.19
Molecular Formula: C43H67N11O12S2
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Atosiban is a peptide oxytocin receptor inhibitor.


References

Tahara, A., et al., Pharmacologic characterization of the oxytocin receptor in human uterine smooth muscle cells. Br. J. Pharmacol. 129, 131-139, (2000) Engstrom, T., et al., Effect of oxytocin receptor blockade on rat myometrial responsivenesss to prostaglandin F2å. Biol. Reprod. 63, 1443-1449, (2000) Wellnitz, O., et al., Atosiban, an oxytocin receptor blocking agent: pharmacokinetics and inhibition of milk ejection in dairy cows. J. Dairy Res. 66, 1-8, (1999)

Physical State :
Solid
Solubility :
Soluble in water: ≤100 mg/mL
Storage :
Desiccate at -20° C
Boiling Point :
~1.3° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5311010
SMILES :
CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSCCC(=O)N[C@@H](C(=O)N1)CC2=CC=C(C=C2)OCC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N)CC(=O)N)[C@@H](C)O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Bartekova M; et al Bartekova M; et al. (PubMed ID: 26323039) determined that Atosiban reversed stress-induced rise in HSP-90 and p53 proteins. -SCBT Publication Review
Date published: 2015-07-05
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