Atorvastatin calcium salt trihydrate is a specific inhibitor of HMGCR (HMG-CoA reductase). HMGCR is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.
Soluble in DMSO (100 mM), and methanol (10 mg/ml). Insoluble in ethanol, and water.
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what is the Formula Weight?
Asked by: RAAD
Formula weight is synonymous to molecular weight. The ratio of Atorvastatin:Calcium:Water is 1:0.5:1.5. Therefore, for one molecule of Atorvastatin the MW is 604.69. The formula and MW we advertise on our product page is for two molecules. The MW in this case is 1209.38.
Answered by: Technical Support
Date published: 2019-01-26
What is the solubility of this product in DMSO?
Asked by: hawkeye11
Thank you for your question.
The solubility of this compound is 10 mg/ml in both DMSO and methanol, for a concentration of 100 mM.
Please contact Technical Service if you have further questions concerning this product.
Rated 5 out of
ZemankovaZemankova, L. et al. (PubMed 26084222) reported that Atorvastatin-induced endothelial nitric oxide synthase expression in endothelial cells is mediated by endoglin. -SCBT Publication Review
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