AT9283An inhibitor of Aurora A, Aurora B, JAK3, JAK2, and c-Abl

AT9283 (CAS 896466-04-9)

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Synonym: 1-cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
Application: An inhibitor of Aurora A, Aurora B, JAK3, JAK2, and c-Abl
CAS Number: 896466-04-9
Molecular Weight: 381.43
Molecular Formula: C19H23N7O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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AT9283 is a potent pan-Aurora inhibitor for Aurora A (IC50 = 3 nM), Aurora B (IC50 = 3 nM), JAK3 (IC50 = 1.1 nM), JAK2 (IC50 = 1.2 nM), and c-Abl (IC50 = 4 nM).

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11696609
SMILES :
C1CC1NC(=O)NC2=CNNC2=C3N=C4C=CC(=CC4=N3)CN5CCOCC5

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Certificate of Analysis

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