Arecaidine propargyl ester tosylate is a potent mAChR M agonist. It shows some selectivity for cardiac, versus ileal mAChR M2.
1. Barlow, R.S., et al. 1985. Br. J. Pharmacol. 85: 437-440. PMID: 3896364 2. Moser, U., et al. 1989. Br. J. Pharmacol. 96: 319-324. PMID: 2924082
Soluble in water (100 mM).
Store at room temperature
pKb: 7.68 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Our lab ordered APE to apply it to rabbits through infusion. Almost every rabbit presented the manifestations of lacking O2. And one rabbit died because of this. We wonder if APE activated the M2 receptor on bronchial smooth muscle, do you know how to ..
Asked by: JIELIN
Thank you for your question. Unfortunately our compounds are not pharmaceutical grade and not manufactured under GMP guidelines, so they are not recommended or warrantied for in vivo animal use. Please consult your principal investigator and your animal care and use committee (ACUC) regarding the use of our biochemical compounds.
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