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Ansatrienin B is an ansamycin antibiotic isolated from Streptomyces, and contains a triene structure. It displays antitumor antibiotic activity, potentiating significantly the action of many clinical antitumor agents. It also displays potent anticancer activities. Ansatrienin B has been reported to inhibit parathyroid hormone-stimulated bone resorption in a concentration-dependent manner.
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