Annexin VIII Antibody (F-12) is a mouse monoclonal IgG2b (kappa light chain) provided at 200 µg/ml
specific for an epitope mapping between amino acids 297-326 at the C-terminus of Annexin VIII of human origin
recommended for detection of Annexin VIII of human origin by WB, IP, IF and ELISA
m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Annexin VIII Antibody (F-12) for WB applications. These reagents are now offered in bundles with Annexin VIII Antibody (F-12) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The annexin family is composed of at least ten mammalian genes that encode calcium-binding proteins. The annexin proteins are characterized by a conserved core domain, which binds to phospholipids in a calcium-dependent manner. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin V is ubiquitously expressed at high levels in tissues and cells grown in tissue culture, while Annexin VIII exhibits a more limited distribution. Where coexpressed in the same tissues, Annexin VIII is often expressed at a 100-fold lower level than Annexin V. However, Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells, which may relate to its role in hematopoietic cell differentiation. At this time it is believed that there are duplicated copies of ANXA8-like genes on human chromosome 10q11 which putatively encode 3 highly similar proteins designated ANXA8L1 and ANXA8L2 (Annexin A8-like 1 and Annexin A8-like 2).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.