Annexin VI Antibody (E-5) is a mouse monoclonal IgG1 κ Annexin VI antibody, cited in 6 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 5-27 at the N-terminus of Annexin VI of human origin
Annexin VI Antibody (E-5) is recommended for detection of Annexin VI of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Annexin VI Antibody (E-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Annexin VI (E-5): sc-271859.
m-IgGκ BP-HRP is the preferred secondary detection reagent for Annexin VI Antibody (E-5) for WB and IHC(P) applications. This reagent is now offered in a bundle with Annexin VI Antibody (E-5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Annexin VI Antibody (E-5) is a high quality monoclonal Annexin VI antibody (also designated ANXA6 antibody, Annexin A6 antibody, Chromobindin-20 antibody, Lipocortin VI antibody, Calphobindin II antibody or 67 kDa calelectrin antibody) suitable for the detection of the Annexin VI protein of mouse, rat and human origin. Annexin VI Antibody (E-5) is available as both the non-conjugated anti-Annexin VI antibody form, as well as multiple conjugated forms of anti-Annexin VI antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca++-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A-431 cells, Annexin VI causes a partial reversal of the transformed phenotype. It has been hypothesized that growth-dependent posttranslational modifications of Annexins are required for proper sub-cellular localization. Annexin VII, also referred to as synexin, is located at the plasma membrane in nor-mal muscle tissue. However, in muscle samples from patients suffering from Duchenne′s muscular dystrophy, Annexin VII, along with Annexins IV and VI, is released into the cytoplasm and later, as the disease progresses, into the extracellular space. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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