Ancitabine hydrochlorideAn antineoplastic agent

Ancitabine hydrochloride (CAS 10212-25-6)

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Application: An antineoplastic agent
CAS Number: 10212-25-6
Molecular Weight: 261.66
Molecular Formula: C9H11N3O4•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ancitabine hydrochloride is an antineoplastic agent.


References

1. Nakamura, K., et al., 1990. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. Journal of medical virology. 31(2): 141-7. PMID: 1696958

Physical State :
Solid
Solubility :
Soluble in water.
Storage :
Store at -20° C
Melting Point :
248-250° C
Boiling Point :
422.18° C
Density :
2.01 g/cm3
Refractive Index :
n20D 1.85
Optical Activity :
α20/D -21.8°, c = 2 in water
IC50 :
B-cell specific antigen receptor-induced NF-kB activation: IC50 = 640 nM (Jurkat cells ); Streptokinase A: EC5050 = 4.89 µM (Streptococcus pyogenes serotype M1); Cytotoxic to Streptococcus: EC5050 = 53.11 µM; B-cell specific antigen receptor-induced NF-kB activation: IC50 = >80 µM (HEK-293T cell line)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
LV2615000
PubChem CID :
16757841
Merck Index :
14: 629
MDL Number :
MFCD00012636
EC Number :
233-515-6
Beilstein Registry :
4166706
SMILES :
C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl

Download SDS (MSDS)

Certificate of Analysis

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