AmrubicinAn inhibitor of DNA topoisomerase II

Amrubicin (CAS 110267-81-7)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 56ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: An inhibitor of DNA topoisomerase II
CAS Number: 110267-81-7
Molecular Weight: 483.47
Molecular Formula: C25H25NO9
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Amrubicin is a synthetic anthracycline antibiotic. It inhibits Topo II (DNA topoisomerase II). Antineoplastic.


References

Igarashi, J., et al.: Bioorg. Med. Chem Lett., 5, 2923 (1995), Hanada, M., et al.: Jpn. J. Cancer Res., 89, 1229 (1998), Ohe, Y., et al.: Ann. Oncol., 16, 430 (2005), Matsunaga, Y., et al.: Ther. Drug Monit., 28, 76 (2006),

Physical State :
Solid
Solubility :
Soluble in Chloroform
Storage :
Store at -20° C
Melting Point :
311.87° C (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3035016
SMILES :
CC(=O)C1(CC(C2=C(C3=C(C(=C2C1)O)C(=O)C4=CC=CC=C4C3=O)O)OC5CC(C(CO5)O)O)N

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Amrubicin  Product Citations

See how others have used Amrubicin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25843419  Chen, J. et al. 2015. Arch. Biochem. Biophys. 575: 38-45.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 51ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 32ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.