AMPK Activator is a furancarboxylic acid derivative that can permeate the cell and partially inhibit the mitochondrial complex I. Research shows that AMPK Activator increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells (sc-2220). In multiple myeloma cells, AMPK Activator inhibits cell growth.
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An increase in MAP LC3 protein expression in PCAn increase in MAP LC3 protein expression in PC-3 cells was observed by WB when comparing untreated and AMPK Activator treated cells. -SCBT QC
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