AMN082 dihydrochlorideA selective agonist at mGluR-7

AMN082 dihydrochloride (CAS 83027-13-8)

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Synonym: N,N'-dibenzhydrylethane-1,2-diamine dihydrochloride; AMN082
Application: A selective agonist at mGluR-7
CAS Number: 83027-13-8
Molecular Weight: 465.46
Molecular Formula: C28H28N22HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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AMN082 Dihydrochloride is a potent and selective agonist at mGluR-7, acting at an allosteric site. mGluR-7 is a metabotropic glutamate receptor 7. AMN082 has been shown to promote the proliferation and differentiation of neural progenitor cells.


References

1. Mitsukawa, K., et al. 2005. Proc. Natl. Acad. Sci. U.S.A. 102: 18712-18717. PMID: 16339898
2. Li, X., et al. 2010. J Neurochem. PMID: 20534005
3. Tian, Y., et al. 2010. Neurochem Int. 57: 8-15. PMID: 20399820

Physical State :
Solid
Solubility :
Soluble in DMSO (10 mg/ml), 100% ethanol, methanol (10 mM), and water.
Storage :
Desiccate at 4° C
Boiling Point :
533.7° C at 760 mmHg (Predicted)
pK Values :
pKb: 8.38
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
11698390
MDL Number :
MFCD08702723
SMILES :
C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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