AMN082 Dihydrochloride is a potent and selective agonist at mGluR-7, acting at an allosteric site. mGluR-7 is a metabotropic glutamate receptor 7. AMN082 has been shown to promote the proliferation and differentiation of neural progenitor cells.
1. Mitsukawa, K., et al. 2005. Proc. Natl. Acad. Sci. U.S.A. 102: 18712-18717. PMID: 16339898 2. Li, X., et al. 2010. J Neurochem. PMID: 20534005 3. Tian, Y., et al. 2010. Neurochem Int. 57: 8-15. PMID: 20399820
Soluble in DMSO (10 mg/ml), 100% ethanol, methanol (10 mM), and water.
Desiccate at 4° C
533.7° C at 760 mmHg (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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