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Ammonium carbamate (CAS 1111-78-0)

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Alternate Names:
Carbamic acid ammonium salt
Application:
Ammonium carbamate is necessary for both the urea cycle and the production of pyrimidines
CAS Number:
1111-78-0
Purity:
99%
Molecular Weight:
78.07
Molecular Formula:
CH3NO2•NH3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ammonium carbamate is a salt formed by the reaction of ammonia with carbon dioxide or carbamic acid. Ammonium carbamate can play a key role in the formation of carbamoyl phosphate, which is necessary for both the urea cycle and the production of pyrimidines. In this enzyme-catalyzed reaction, ATP and ammonium carbamate are converted to ADP and carbamoyl phosphate. Ammonium carbamate is used as an inert ingredient in aluminum phosphide pesticide formulations functioning to make the phosphine less flammable by freeing ammonia and carbon dioxide to dilute hydrogen phosphide formed by a hydrolysis reaction. It can also be used as a good ammoniating agent, but not nearly as strong an ammoniating agent as ammonia. Ammonium carbamate has also been used in Glycoblotting, a high throughput method for N-glycan enrichment, proven to be feasible for selective enrichment analysis of O-glycans of common (mucin) glycoproteins.


Ammonium carbamate (CAS 1111-78-0) References

  1. Effect of ammonium carbamate on nutritive and preservative characteristics of high-moisture coastal bermudagrass hay.  |  Johnson, LJ., et al. 1991. J Anim Sci. 69: 2608-16. PMID: 1653198
  2. Glycoblotting-assisted O-glycomics: ammonium carbamate allows for highly efficient o-glycan release from glycoproteins.  |  Miura, Y., et al. 2010. Anal Chem. 82: 10021-9. PMID: 21077635
  3. Visible-light-driven catalytic oxidation of aldehydes and alcohols to nitriles by 4-acetamido-TEMPO using ammonium carbamate as a nitrogen source.  |  Nandi, J. and Leadbeater, NE. 2019. Org Biomol Chem. 17: 9182-9186. PMID: 31595927
  4. Formation Mechanism of Ammonium Carbamate for CO2 Uptake in N,N'-Dimethylethylenediamine Grafted M2(dobpdc).  |  Zhang, H., et al. 2020. Langmuir. 36: 14104-14112. PMID: 33170717
  5. Catalytic Urea Synthesis from Ammonium Carbamate Using a Copper(II) Complex: A Combined Experimental and Theoretical Study.  |  Hanson, DS., et al. 2021. Inorg Chem. 60: 5573-5589. PMID: 33826330
  6. Divergent Synthesis of 2-Cyanoaryl Carbamate and 2-Cyanoaryl Urea Derivatives via Hypervalent Iodine-Induced C-C Bond Cleavage.  |  Wang, K., et al. 2022. J Org Chem. 87: 10208-10215. PMID: 35861605
  7. A scalable solid-state nanoporous network with atomic-level interaction design for carbon dioxide capture.  |  Mao, H., et al. 2022. Sci Adv. 8: eabo6849. PMID: 35921416
  8. Ultrasensitive and Selective Detection of Glutathione by Ammonium Carbamate-Gold Platinum Nanoparticles-Based Electrochemical Sensor.  |  Wang, W., et al. 2022. Life (Basel). 12: PMID: 36013320
  9. Late-stage diversification of indole skeletons through nitrogen atom insertion.  |  Reisenbauer, JC., et al. 2022. Science. 377: 1104-1109. PMID: 36048958
  10. Building the uracil skeleton in primitive ponds at the origins of life: carbamoylation of aspartic acid.  |  Ter-Ovanessian, LMP., et al. 2022. Sci Rep. 12: 19178. PMID: 36357418
  11. Synthesis of Sulfoximines and Sulfonimidamides Using Hypervalent Iodine Mediated NH Transfer.  |  Luisi, R. and Bull, JA. 2023. Molecules. 28: PMID: 36770787
  12. Mixed Diethanolamine and Polyethyleneimine with Enhanced CO2 Capture Capacity from Air.  |  Miao, Y., et al. 2023. Adv Sci (Weinh). 10: e2207253. PMID: 37017566
  13. Toxicologic effects of ammonium carbamate and related compounds.  |  Wilson, RP., et al. 1968. Am J Vet Res. 29: 897-906. PMID: 5689272

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ammonium carbamate, 25 g

sc-223777
25 g
$26.00

Ammonium carbamate, 100 g

sc-223777A
100 g
$51.00