α-Zearalenol is a synthetic derivative of the macrolactone mycotoxin zearalenone (sc-204943) isolated from the Fusarium roseum fungus. α-Zearalenol is estrogenically active and demonstrates induction of premature uterine growth, increase of nuclear estrogen receptor levels, and a five fold increase of ornithine decarboxylase level (ODC). The increase of ODC level was 20-fold more pronounced with α-zearalenol than zearalenone, and α-Zearalenol demonstrated three times more potent estrogenic activity than zearalenone.
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See how others have used alpha-Zearalenol (CAS 36455-72-8). Click on the entry to view the PubMed entry .
PMID: # 26255852 Nakamura, U. et al. 2015. Theriogenology. 84: 1342-9.
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