Aloe-emodin shows significant inhibitory activity against the P-388 leukemia in mice when administered as a suspension in acetone-Tween 80. Has a specific in vitro and in vivo antineuroectodermal tumor activity.
Hung, K., et al.: J. Exp. Med., 188, 2357 (1998), Gazzola, P.T., et al.: Cancer Res., 60, 2800 (2000), Irie, T., et al.: Int. J. Cancer, 121, 8784 (2007), Zhao, J., et al.: Eur. J. Neurol., 14, 510 (2007),
Soluble in water (partly), hot alcohol, methanol, chloroform, and DMSO (50 mg/ml).
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