Molecular structure of Allopurinol riboside, CAS Number: 16220-07-8
Allopurinol riboside (CAS 16220-07-8)
Alternate Names:
8-Aza-7-deazainosine; 1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4-one
Application:
Allopurinol riboside is a structural isomer of hypoxanthine
CAS Number:
16220-07-8
Purity:
≥95%
Molecular Weight:
268.23
Molecular Formula:
C10H12N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Allopurinol is a structural isomer of hypoxanthine, a naturally occurring purine in the body. It is also an enzyme inhibitor of xanthine oxidase and an anti-leishmanial agent.
Allopurinol riboside (CAS 16220-07-8) References
- Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. | Pacher, P., et al. 2006. Pharmacol Rev. 58: 87-114. PMID: 16507884
- Pharmacokinetics and metabolism of allopurinol riboside. | Shapiro, TA., et al. 1991. Clin Pharmacol Ther. 49: 506-14. PMID: 2029827
- Treatment of American cutaneous leishmaniasis with orally administered allopurinol riboside. | Saenz, RE., et al. 1989. J Infect Dis. 160: 153-8. PMID: 2659681
- Perspectives on research and diseases of the Tropics: an Asian view. | Ramalingaswami, V. 1989. Ann N Y Acad Sci. 569: 25-35. PMID: 2698093
- An association study of ABCG2 rs2231142 on the concentrations of allopurinol and its metabolites. | Pilon, MO., et al. 2022. Clin Transl Sci. 15: 2024-2034. PMID: 35689378
- A Genome-Wide Association Study of Oxypurinol Concentrations in Patients Treated with Allopurinol. | Meloche, M., et al. 2024. J Pers Med. 14: PMID: 38929870
- Inosine analogs. Their metabolism in mouse L cells and in Leishmania donovani. | LaFon, SW., et al. 1985. J Biol Chem. 260: 9660-5. PMID: 4019491
- Allopurinol ribonucleoside as an antileishmanial agent. Biological effects, metabolism, and enzymatic phosphorylation. | Nelson, DJ., et al. 1979. J Biol Chem. 254: 11544-9. PMID: 500658
- Metabolic studies of high doses of allopurinol in humans. | Nelson, DJ. and Elion, GB. 1984. Adv Exp Med Biol. 165 Pt A: 167-70. PMID: 6720373
- Effects of probenecid on the pharmacokinetics of allopurinol riboside. | Were, JB. and Shapiro, TA. 1993. Antimicrob Agents Chemother. 37: 1193-6. PMID: 8517715
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Allopurinol riboside, 25 mg | sc-217610 | 25 mg | $150.00 | |||
Allopurinol riboside, 1 g | sc-217610A | 1 g | $2290.00 |