Alizarin Red S CAS: 130-22-3
MF: C14H7O7S•Na
MW: 342.26
Used to determine the presence of calcific deposition by cells of an osteogenic lineage.

Alizarin Red S (CAS 130-22-3)

Alizarin Red S | CAS 130-22-3 is rated 5.0 out of 5 by 1.
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Alternate Names: Sodium Alizarinesulfonate; Mordant Red 3; Alizarin Carmine
Application: Alizarin Red S is used to determine the presence of calcific deposition by cells of an osteogenic lineage
CAS Number: 130-22-3
Molecular Weight: 342.26
Molecular Formula: C14H7O7S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Alizarin Red S is used in a biochemical assay to determine, quantitatively by colorimetry, the presence of calcific deposition by cells of an osteogenic lineage. Alizarin Red S has also been used as a histochemical stain for calcium in cells of non-osteogenic lineage and also a colorometric pH indicator in the range of 3.8-5.4.


References

1. Bertoni, L., et al. 2009. J. Anat. 215: 577-583. PMID: 19682137
2. Verma, D., et al. 2010. Philos Transact A Math Phys Eng Sci. 368: 2083-2097. PMID: 20308116

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (1 mg/mL).
Storage :
Store at 4° C
Melting Point :
287-289° C
Boiling Point :
430° C
IC50 :
Protein-tyrosine phosphatase 1B: IC50 = 40 µM (human); Protein-tyrosine phosphatase 1: IC50 = 48 µM (Saccharomyces cerevisiae S288c)
pK Values :
pKa: -1.33 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
CB1095300
PubChem CID :
Merck Index :
14: 8573
MDL Number :
MFCD00013049
EC Number :
204-981-8
Beilstein Registry :
4117090
SMILES :
C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)O)S(=O)(=O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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Alizarin Red S (CAS 130-22-3)  Product Citations

See how others have used Alizarin Red S (CAS 130-22-3). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 12 total

PMID: # 34098046  Çil, N.|Mete, GA.| et al. 2021. Reprod Toxicol. 103: 71-78.

PMID: # 34013634  Azimifar, MA.|Salmasi, Z.|Doosti, A.|Babaei, N.|Hashemi, M.| et al. 2021. Biotechnol Prog. e3175.

PMID: # 32052657  Kang, Y.|Guo, S.|Sun, Q.|Zhang, T.|Liu, J.|He, D.| et al. 2020. Epigenomics. 12: 289-302.

PMID: # 30563251  Lin, SY.|Kang, L.|Wang, CZ.|Huang, HH.|Cheng, TL.|Huang, HT.|Lee, MJ.|Lin, YS.|Ho, ML.|Wang, GJ.|Chen, CH.| et al. 2018. Molecules. 23:

PMID: # 28000839  Liu, W.|Sun, Y.|He, Y.|Zhang, H.|Zheng, Y.|Yao, Y.|Zhang, Z.| et al. 2017. Int. J. Mol. Med. 39: 317-326.

PMID: # 27075964  Yang, Q.|Chen, X.|Zheng, T.|Han, D.|Zhang, H.|Shi, Y.|Bian, J.|Sun, X.|Xia, K.|Liang, X.|Liu, G.|Zhang, Y.|Deng, C.| et al. 2016. Cell Transplant. 25: 1987-2001.

PMID: # 26880937  Maioli, M.|Basoli, V.|Santaniello, S.|Cruciani, S.|Delitala, AP.|Pinna, R.|Milia, E.|Grillari-Voglauer, R.|Fontani, V.|Rinaldi, S.|Muggironi, R.|Pigliaru, G.|Ventura, C.| et al. 2016. Stem Cells Int. 2016: 2056416.

PMID: # 21354907  Lu, GH. et al. 2011. Nan Fang Yi Ke Da Xue Xue Bao. 31: 262-265.

PMID: # 31582984  Stem Cells Int. 2019: 2168709.

PMID: # 32410328  Biotechnol. Prog. e3025.

Citations 1 to 10 of 12 total

Hi, please advise the availability of ALIZARIN RED S 25g, in stock, lag time .

Asked by: Xingting
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, please contact Customer Service.
Answered by: Tech Service
Date published: 2019-08-20
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Rated 5 out of 5 by from Various publications cite the use of Alizarin Various publications cite the use of Alizarin Red S in biochemical assays to determine, quantitatively by colorimetry, the presence of calcific deposition by cells of an osteogenic lineage. Alizarin Red S has also been used as a histochemical stain for calcium in cells of non-osteogenic lineage and also a colorometric pH indicator in the range of 3.8-5.4. -SCBT Publication Review
Date published: 2015-03-19
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