Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. The family of RII-anchoring proteins has been designated A-kinase anchoring proteins (AKAP). AKAP 8, also known as AKAP 95, is a nuclear matrix protein predominantly expressed in liver, heart, pancreas, kidney and skeletal muscle. During mitosis, AKAP 8 is recruited to the chromosomes and plays an essential role in mitotic progression. AKAP 8L (AKAP 8-like), also known as HA95 (homologous to AKAP 95 protein), HAP95 (Helicase A-binding protein 95), NAKAP or NAKAP95 (neighbor of AKAP 95), is also a nuclear matrix protein and shares 61% homology and 30% identity with AKAP 8. In addition, AKAP 8L forms a complex with AKAP 8 and HDAC3 and is required for the deacetylation of Histone H3 in mitosis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.