Agmatine sulfateAn L-arginine decarboxy analog with neurotransmiter activity

Agmatine sulfate (CAS 2482-00-0)

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Application: An L-arginine decarboxy analog with neurotransmiter activity
CAS Number: 2482-00-0
Purity: ≥98%
Molecular Weight: 228.27
Molecular Formula: C5H14N4•H2SO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Agmatine sulfate is the sulfate preparation of Agmatine, the decarboxylated form of L-arginine and an endogenous metabolic product highly conserved across life forms. Agmatine is an intermediate in the biosynthesis of the polyamines putrescine and spermine. Agmatine binds with high affinity to α2-adrenergic receptors and imidazoline binding sites and produces blockade of the NMDA-receptor associated cation channels. The further observations that Agmatine is also stored in synaptic vesicles, is specifically degraded by agmatinase, and is released from axon terminals by depolarization all suggest that Agmatine has endogenous function as a neurotransmitter. Agmatine is a competitive inhibitor of NOS (nitric oxide synthase) activity owing to mimicry of the natural NOS substrate arginine.


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Physical State :
Solubility :
Soluble in water (50 mg/ml). Insoluble in ethanol.
Storage :
Store at -20° C
Melting Point :
234-238° C (lit.)
Boiling Point :
281.4° C at 760 mmHg (Predicted) (tautomer)
Refractive Index :
n20D 1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 188
MDL Number :
EC Number :
Beilstein Registry :

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Certificate of Analysis

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