Adrenic Acid (22:4, n-6) CAS: 28874-58-0
MF: C22H36O2
MW: 332.5
A polyunsaturated fatty acid believed to be a source of arachidonic acid.

Adrenic Acid (22:4, n-6) (CAS 28874-58-0)

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Synonym: cis-7,10,13,16-Docosatetraenoic acid
Application: A polyunsaturated fatty acid believed to be a source of arachidonic acid
CAS Number: 28874-58-0
Purity: ≥96%
Molecular Weight: 332.5
Molecular Formula: C22H36O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Adrenic Acid (22-4,n-6), also known as 7,10,13,16-Docosatetraenoic acid, is a polyunsaturated fatty acid. Peroximal β-oxidation of 7,10,13,16-docosatetraenoic acid has been shown to form arachidonic acid. Endothelial cells have been shown to convert arachidonic acid to docosatetraenoic acid and releasing docosatetraenoic acid when exposed to ionophore A23187 (sc-3591). Additionally, endothelial cell studies have demonstrated that adrenic acid reduces prostaglandin 12.


References

1. Campbell, W.B., et al. 1985. Biochim. Biophys. Acta. 837: 67-76. PMID: 3931686
2. Mann, C.J., et al. 1986. Arch. Biochem. Biophys. 244: 813-823. PMID: 3080955
3. Baykousheva, S.P., et al. 1994. J. Biol. Chem. 269: 18390-18394. PMID: 8034586
4. Krämer, S.D., et al. 2002. In Vitro Cell. Dev. Biol. Anim. 38: 566-571. PMID: 12762838
5. McNamara, R.K., et al. 2010. Eur J Pharmacol. [Epub ahead of print]. PMID: 21118685

Appearance :
Oil
Physical State :
Liquid
Solubility :
Soluble in ethanol, hexane, methylene chloride, DMSO (100 mg/ml), DMF (100 mg/ml), and PBS pH 7.4. Insoluble in water.
Storage :
Store at -20° C
Boiling Point :
439.49° C at 760 mmHg
Density :
0.92 g/mL
Refractive Index :
n20D 1.50
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
5497181
MDL Number :
MFCD00673435
SMILES :
CCCCCC=CCC=CCC=CCC=CCCCCCC(=O)O

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Certificate of Analysis

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Adrenic Acid (22:4, n-6)  Product Citations

See how others have used Adrenic Acid (22:4, n-6). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 21118685  McNamara, RK. et al. 2011. Eur. J. Pharmacol. 652: 152-156.

Citations 1 to 1 of 1 total
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