A potent, noncompetitive and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG) (IC50=120nM) versus ADP-ribose (IC50=120µM). This compound does not affect the activities of either PARP-1 or NAD:arginine mono(ADP-ribosyl)-transferase A even at 1mM concentration.
J.T. Slama, et al.; J. Med. Chem. 38, 389 (1995) J.T. Slama, et al.; J. Med. Chem. 38, 4332 (1995) S. Vispe, et al.; PNAS 97, 9886 (2000)
Following reconstitution, prepare aliquots and store at -20°C.
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
Vilchez LarreaVilchez Larrea, SC. Et al. (PubMed 23776710) used the potent, noncompetitive and specific inhibitor of poly(ADP-ribose) glycohydrolase ADP-HPD to demonstrate that host cell poly(ADP-ribose) glycohydrolase is critical for Trypanosoma cruzi infection cycle. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.