Adenosine 5′-triphosphate, periodate oxidized sodium salt (CAS 71997-40-5)
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Adenosine 5′-triphosphate, periodate oxidized sodium salt (Oxidized ATP) is a chemical compound derived from ATP (adenosine triphosphate), a molecule essential for cellular energy transfer. The periodate oxidation modifies the ATP molecule, making it an antagonist of the P2X(7) receptor, a subtype of purinergic receptors. P2X(7) receptors are involved in various physiological processes, including inflammation, cell death, and neurotransmission. Oxidized ATP binds to P2X(7) receptors, inhibiting their activity and reducing downstream signaling. This makes it a useful tool for studying the P2X(7) pathway and its roles in various biological processes. Additionally, oxidized ATP can be used to assess the activity of P2X(7) receptors by measuring the mobilization of intracellular calcium ions (Ca2+). It is important to note that oxidized ATP is a non-specific agonist, meaning it can activate other P2X receptors besides P2X(7). Its specificity for P2X(7) is dependent on the concentration used. Overall, oxidized ATP is a valuable pharmacological tool for understanding the physiology and pathophysiology of P2X(7) receptors. Its use has contributed significantly to the understanding of purinergic signaling and its roles in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenosine 5′-triphosphate, periodate oxidized sodium salt, 25 mg | sc-214508 | 25 mg | $234.00 | |||
Adenosine 5′-triphosphate, periodate oxidized sodium salt, 100 mg | sc-214508A | 100 mg | $754.00 |