Adenosine 5'-[γ-thio]triphosphate tetralithium saltA P2 purinergic receptor agonist that increases activity of Ca2+-activated K+ channels

Adenosine 5′-[γ-thio]triphosphate tetralithium salt (CAS 93839-89-5)

Adenosine 5′-[γ-thio]triphosphate tetralithium salt | CAS 93839-89-5 is rated 5.0 out of 5 by 1.
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Synonym: Adenosine 5'-O-(3-thiotriphosphate), tetralithium; Ado-5′-PPP[S]; ATP-γ-S
Application: A P2 purinergic receptor agonist that increases activity of Ca2+-activated K+ channels
CAS Number: 93839-89-5
Purity: ≥85%
Molecular Weight: 546.98
Molecular Formula: C10H12N5O12P3S•4Li
* Refer to Certificate of Analysis for lot specific data (including water content).
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Adenosine 5'-[γ-thio]triphosphate tetralithium salt is a P2 purinergic receptor agonist that increases activity of Ca2+-activated K+ channels. It can be used as an ATP analog in kinase reactions yielding thiophosphorylated proteins which are resistant to protein phosphatases.


References

Chrysogelos, S., et al. J. Biol. Chem. 258, 12624, (1983) Goody, R. S., et al. Biochim. Biophys. Acta 276, 155, (1972) Goody, R. S., and Eckstein, F. J. Am. Chem. Soc. 93, 6252, (1971)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (10 mg/ml).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
MDL Number :
MFCD00077293
EC Number :
298-862-8
Beilstein Registry :
6265083
SMILES :
[Li+].[Li+].[Li+].[Li+].C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O

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Certificate of Analysis

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Rated 5 out of 5 by from Consistent results with previous experiments Consistent results with previous experiments.
Date published: 2015-03-30
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