Adenosine 3prime-phosphate 5prime-phosphosulfate lithium saltA commonly used sulfonate donor

Adenosine 3′-phosphate 5′-phosphosulfate lithium salt (CAS 109434-21-1)

Adenosine 3′-phosphate 5′-phosphosulfate lithium salt | CAS 109434-21-1 is rated 5.0 out of 5 by 1.
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Synonym: 3′-Phosphoadenosine 5′-phosphosulfate lithium salt; APPS; Active sulfate; PAPS
Application: A commonly used sulfonate donor
CAS Number: 109434-21-1
Purity: ≥60%
Molecular Weight: 507.26
Molecular Formula: C10H15N5O13P2S•xLi
* Refer to Certificate of Analysis for lot specific data (including water content).
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Adenosine 3'-phosphate 5'-phosphosulfate lithium salt is a commonly used sulfonate donor for sulfonation of glycans. It is also useful to study the distribution and function of its biological transporters. Adenosine 3'-phosphate 5'-phosphosulfate lithium salt has been used to assess the golgi-resident PAP-specific 3′-phosphatase-coupled sulfotransferase assays.


References

1. Horwitz, J.P. et al. 1977. Biochim. Biophys. Acta. 480(2): 376-381. PMID: 189816

2. Zhou, X. et al. 2011. Glycobiology. 21(6): 771-780. PMID: 21224284

3. Dawson, P.A. 2011. Semin. Cell Dev. Biol. 22(6): 653-659. PMID: 21419855

4. Prather, B. et al. 2012. Anal. Biochem. 423(1): 86-92. PMID: 22289690

Usage :
Product will degrade if not kept at -20°C.
Appearance :
Powder
Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
77620750
SMILES :
[Li+].[Li+].[Li+].[Li+].C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OS(=O)(=O)[O-])OP(=O)([O-])[O-])O.O

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Adenosine 3prime-phosphate 5prime-phosphosulfate lithium salt  Product Citations

See how others have used Adenosine 3prime-phosphate 5prime-phosphosulfate lithium salt. Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 31605160  2019. Arch. Toxicol.

PMID: # 29588428  Zimmer, B.|Tenbusch, L.|Klymiuk, MC.|Dezhkam, Y.|Schuler, G.| et al. 2018. J. Mol. Endocrinol. 61: M41-M55.

PMID: # 26660633  Fang, JL. et al. 2016. Toxicol. Sci. 150: 27-39.

Citations 1 to 3 of 3 total

If sc-210759 has a purity of only ≥ 60%. What are the impurities of the remaining product?

Asked by: Chemsynth123
Thank you for your question. When Adenosine 3'-phosphate 5'-phosphosulfate lithium salt, sc-210759, decomposes impurities such as adenosine 3′,5′-diphosphate, sulfate and ammonia substitution products can form. Storing sc-210759 at -20ºC and minimizing exposure time at room temperature will prevent formation of these impurities.
Answered by: TechService7
Date published: 2017-06-22
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Rated 5 out of 5 by from This product seems to work very well This product seems to work very well.
Date published: 2015-06-16
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