Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrateA PKA (protein kinase A) activator

Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate (CAS 37839-81-9)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 70ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: cAMP-Na; Cyclic AMP Sodium Salt
Application: A PKA (protein kinase A) activator
CAS Number: 37839-81-9
Purity: ≥98%
Molecular Weight: 369.20
Molecular Formula: C10H11N5NaO6P · H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is a naturally-occurring activator of PKA (cAMP-dependent protein kinase A). Cyclic-AMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has shown to induce differentiation, inhibit cell proliferation, and lead to apoptosis. Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is an activator of Epac.


References

1. Spada, A., et al. 1997. Horm. Res. 47: 235-239. PMID: 9167957
2. Daniel, P.B., et al. 1998. Annu. Rev. Nutr. 18: 353-383. PMID: 9706229
3. Chen, T.C., et al. 1998. Lab. Invest. 78: 165-174. PMID: 9484714

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml).
Storage :
Store at -20° C
pK Values :
pKa: 1 (Predicted), pKb: 3.63 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
PubChem CID :
23669773
MDL Number :
MFCD00069736
Beilstein Registry :
54612
SMILES :
C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 71ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 5ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.