Anti-ADAM22 Antibody (C-2) is a mouse monoclonal IgG1 κ ADAM22 antibody, cited in 4 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 286-319 within an internal region of ADAM22 of human origin
Anti-ADAM22 Antibody (C-2) is recommended for detection of ADAM22 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-ADAM22 Antibody (C-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ADAM22 (C-2): sc-373931.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ADAM22 Antibody (C-2). This work is in progress.
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Labware ships FedEx Ground free of charge to the contiguous US
ADAM22 Antibody (C-2) is a high quality monoclonal ADAM22 antibody (also designated MDC2 antibody) suitable for the detection of the ADAM22 protein of mouse, rat and human origin. ADAM22 Antibody (C-2) is available as both the non-conjugated anti-ADAM22 antibody form, as well as multiple conjugated forms of anti-ADAM22 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The ADAM (a disintegrin and metalloprotease) protein family, which includes over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases, plays a role in cell-cell and cell-matrix interface related processes, including fertilization, muscle fusion, secretion of TNFα (tumor necrosis factor α), and modulation of the neurogenic function of Notch and Delta. The ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in a wide range of mammalian tissues and several are abundantly expressed in the male reproductive tract. ADAM22 and ADAM23 (designated MDC2 and MDC3, respectively) are structurally similar proteins that contain a disrupted zinc-binding motif, and both are highly expressed in brain. The genes encoding human ADAM22 and ADAM23 map to chromosomes 7q21 and 2q33, respectively.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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