Anti-ACYP2 Antibody (B-3) is a mouse monoclonal IgG2b (kappa light chain) ACYP2 antibody provided at 200 µg/ml
raised against amino acids 1-99 representing full length ACYP2 of human origin
Anti-ACYP2 Antibody (B-3) is recommended for detection of muscle ACYP2 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-ACYP2 Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ACYP2 (B-3): sc-398298.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for ACYP2 Antibody (B-3) for WB applications. These reagents are now offered in bundles with ACYP2 Antibody (B-3) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
ACYP2 Antibody (B-3) is a high quality monoclonal ACYP2 antibody (also designated ACYP2 antibody) suitable for the detection of the ACYP2 protein of mouse, rat and human origin. ACYP2 Antibody (B-3) is available as both the non-conjugated anti-ACYP2 antibody form, as well as multiple conjugated forms of anti-ACYP2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The formation of stable highly organized protein aggegrates, known as amyloid fibrils, is associated with several debilitating human diseases, including Alzheimer′s disease, Parkinson′s disease, and Creutzfeldt-Jakob disease (1,2). In each of these conditions, a peptide or protein that is normally soluble accumulates into insoluble fibrils (1,2). Muscle acylphosphatase (AcP) has emerged as a significant model system to study protein misfolding and aggregation (1,3-6). It is particularly suitable for these studies because muscle AcP is a small, simple protein of only 98 amino acids consisting of a five-stranded antiparallel b-sheet and two parallel a-helices. Mutations in the muscle AcP between residues 16-31 and 87-98, which includes its phosphate binding site at Arg-23, significantly increases the rate of aggregation (1,6). These mutations correlate with changes in the hydrophobicity of AcP and a conversion of the a-helical structures to b-sheets. Therefore, a reduction in the net charge of a protein may be a key determinant in some forms of protein deposition diseases.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences