ABN-CBDAn agonist of the novel cannabinoid receptor GPR55

ABN-CBD (CAS 22972-55-0)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 53ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: Abnormal-cannabidiol
Application: An agonist of the novel cannabinoid receptor GPR55
CAS Number: 22972-55-0
Purity: ≥98%
Molecular Weight: 314.47
Molecular Formula: C21H30O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

ABN-CBD is a neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 (EC50 values are 2.5, >30 and >30 μM at GPR55, CB1 and CB2 receptors respectively). ABN-CBD increases the phosphorylation of protein kinases in, and migration of, human umbilical vein endothelial cells.


References

1. Jarai, Z., et al. 1999. Proc. Natl. Acad. Sci. U.S.A. 96: 14136-14141. PMID: 10570211
2. Ho. W.S. and Hiley, C.R., 2003. Br. J. Pharmacol. 138: 1320-1332. PMID: 12711633
3. Mo, F.M., et al. 2004. Eur. J. Pharmacol. 489: 21-27. PMID: 15063151
4. Ryberg, E., et al. 2007. Br. J. Pharmacol. 152: 1092-1101.PMID: 17876302

Formulation :
A solution in methyl acetate
Physical State :
Liquid
Solubility :
Soluble in methyl acetate, ethanol (~35 mg/ml), DMSO (~35 mg/ml), DMF (~35 mg/ml), and DMSO:PBS (1:3, pH 7.2) (0.25 mg/ml).
Storage :
Desiccate at -20° C
Boiling Point :
57° C
Refractive Index :
n20D 1.55 (Predicted)
Optical Activity :
α20/D -71.8°, c = 0.98 in chloroform
IC50 :
regulate the migratory activity of murine BV-2 microglial cells: EC5050 = 0.6 µM; GPR55: EC5050 = 2.5 µM; CB2 : EC5050 >30 µM; CB1 : EC5050 >30 µM
pK Values :
pKa: 9.95 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
VH1620000
PubChem CID :
89949
MDL Number :
MFCD08705633
SMILES :
CCCCCC1=CC(=CC(=C1[C@@H]2C=C(CC[C@H]2C(=C)C)C)O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 74ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 35ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.