8-Hydroxyquinoline hemisulfate salt hemihydrateA 20S proteasome inhibitor

8-Hydroxyquinoline hemisulfate salt hemihydrate (CAS 207386-91-2)

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Synonym: 8-Quinolinol hemisulfate
Application: A 20S proteasome inhibitor
CAS Number: 207386-91-2
Purity: ≥98%
Molecular Weight: 406.42
Molecular Formula: C18H14N2O2•H2SO4•H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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8-Hydroxyquinoline hemisulfate salt hemihydrate acts as an inhibitor for the chymotrypsin-like activity of the 20S proteasome, as well as a potential copper ligand.


References

1. Daniel, Kenyon G., et al., 2004. Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells. Biochemical pharmacology. 67(6): 1139-51. PMID: 15006550

Appearance :
Powder
Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
176.0-179.0° C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
49853510
SMILES :
O.OS(O)(=O)=O.OC1=C2N=CC=CC2=CC=C1.OC1=C2N=CC=CC2=CC=C1

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Certificate of Analysis

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8-Hydroxyquinoline hemisulfate salt hemihydrate  Product Citations

See how others have used 8-Hydroxyquinoline hemisulfate salt hemihydrate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 28086193  Griesser, E. et al. 2017. Redox Biol. 11: 438-455.

Citations 1 to 1 of 1 total
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