7-Ethyl Camptothecin CAS: 78287-27-1
MF: C22H20N2O4
MW: 376.41
An anti-cancer agent and Topo I inhibitor.

7-Ethyl Camptothecin (CAS 78287-27-1)

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Alternate Names: 7-Ethyl-20(S)-camptothecin
Application: 7-Ethyl Camptothecin is an anti-cancer agent and Topo I inhibitor
CAS Number: 78287-27-1
Molecular Weight: 376.41
Molecular Formula: C22H20N2O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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7-Ethyl Camptothecin is a Camptothecin (sc-200871) derivative. 7-Ethyl Camptothecin is an anti-cancer chemical which exhibited a strong activity against various murine tumors through Topo I (topoisomerase) inhibition.


References

Brangi, M., et al.: Cancer Res., 59 5938 (1999), Miyake, K., et al.: Cancer Res., 59, 8 (1999), Bom, D., et al.: J. Med. Chem., 43, 3970 (2000), Gamcsik, M., et al.: Mol. Cancer Ther., 1, 11 (2001).

Physical State :
Solid
Solubility :
Soluble in DMF, DMSO, and chloroform.
Storage :
Store at -20° C
Melting Point :
236-241° C (lit.)
Boiling Point :
752.87° C at 760 mmHg (Predicted)
Density :
1.44 g/cm3 (Predicted)
Refractive Index :
n20D 1.71 (Predicted)
Optical Activity :
α20/D 43°, c = 0.4 in CHCl3:MeOH=8:2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD06657922
SMILES :
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[[email protected]@]4(CC)O)C2=NC5=CC=CC=C51

Download SDS (MSDS)

Certificate of Analysis

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