7-Deacetyl-7-[O-(N-methylpiperazino)-gamma-butyryl]-Forskolin Dihydrochloride CAS: 115116-37-5
MF: C29H48N2O7 2HCl
MW: 609.6
A modified forskolin that activates adenylate cyclase.

7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-Forskolin Dihydrochloride (CAS 115116-37-5)

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Synonym: L-858051; 8,13-Epoxy-7β-(N-methylpiperazino-γ-butyryloxy)-1α,6β,9α-trihydroxy-labd-14-en-11-one; Adenylate cyclase activator
Application: A modified forskolin that activates adenylate cyclase
CAS Number: 115116-37-5
Molecular Weight: 609.6
Molecular Formula: C29H48N2O7 2HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-Forskolin dihydrochloride is a chemically-modified forskolin with greater stability and water solubility than the parent compound. 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-Forskolin dihydrochloride activates A cyclase (adenylate cyclase) and inhibits 5HT-stimulated inositol phosphate accumulation in muscle cells (smooth).


Yang, C.M., et al. 1999. Cell Signal. 11, 697. Hartzell, H.C., and Budnitz, D. 1992. Mol. Pharmacol. 41, 880. Chidiac, P., et al. 1991. J. Mol. Cell. Cardiol. 23, 1255. Laurenza, A., et al. 1987. Mol. Pharmacol. 32, 133.

Physical State :
Solubility :
Soluble in water (12 mg/ml), and methanol.
Storage :
Store at -20° C
Boiling Point :
685.7° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
IC50 :
A cyclase: EC5050 = 13 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

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Certificate of Analysis

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