7,8-Dihydro-L-biopterinCAS: 6779-87-9
MF: C9H13N5O3
MW: 239.23
A precursor of BH4 synthesis.

7,8-Dihydro-L-biopterin (CAS 6779-87-9)

7,8-Dihydro-L-biopterin | CAS 6779-87-9 is rated 5.0 out of 5 by 1.
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Synonym: BH2; Dihydrobiopterin; Quinonoid dihydrobiopterin
Application: A precursor of BH4 synthesis
CAS Number: 6779-87-9
Purity: ≥98%
Molecular Weight: 239.23
Molecular Formula: C9H13N5O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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7,8-dihydro-L-Biopterin is a precursor of BH4 synthesis and a noncompetitive inhibitor of GCH-I (GTP cyclohydrolase I), with a Ki of 14.4 μM.


References

1 Shen, R., Alam, A., Zhang, Y. Inhibition of GTP cyclohydrolase I by pterins. Biochim Biophys Acta 965 9-15 (1988).

Appearance :
Powder
Physical State :
Solid
Solubility :
Slightly soluble in water (2mg/ml, 22°C, ultrasonication)
Storage :
Store at -20° C
Density :
~1.9 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
119055
SMILES :
C[C@@H]([C@@H](C1=NC2=C(NC1)NC(=NC2=O)N)O)O

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Certificate of Analysis

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7,8-Dihydro-L-biopterin  Product Citations

See how others have used 7,8-Dihydro-L-biopterin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25550200  Yang, S. et al. 2015. J. Pharmacol. Exp. Ther. 352: 529-40.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Crabtree Crabtree, MJ. et al. (PubMed 18192221) reported that the ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-Dihydro-L-biopterin in endothelial cells determines glucose-elicited changes in nitric oxide versus superoxide production by endothelial nitric oxide synthase. -SCBT Publication Review
Date published: 2015-03-12
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