7,12-Dimethylbenz[a]anthracene is a highly potent carcinogen that is activated by microsomal enzymes to a diol epoxide metabolite that binds covalently to DNA in mammalian cells, leading ultimately to tumor induction.
Huggins, C., et al.: Proc. Nat. Acad. Sci. U.S.A., 58, 2253 (1967), Dipple, A., et al.: N. Cancer Res., 43, 4123 (1983),
Soluble in toluene (50 mg/ml), acetone, chloroform, dichloromethane, ethanol, diethyl ether, n-octanol, and hot water (very slightly). Insoluble in cold water.
Store at room temperature
122-123° C (lit.)
463.46° C at 760 mmHg (Predicted)
1.14 g/cm3 (Predicted)
n20D 1.73 (Predicted)
λex 440 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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7,12-Dimethylbenz[a]anthracene Product Citations
See how others have used 7,12-Dimethylbenz[a]anthracene. Click on the entry to view the PubMed entry
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