Date published: 2025-12-7

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6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester (CAS 215312-86-0)

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Alternate Names:
Sulfo-EMCS
Application:
6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester is a water-soluble, heterobifunctional amine- and sulfhydryl-reactive crosslinker, 9.4 angstrom spacer arm
CAS Number:
215312-86-0
Purity:
≥95%
Molecular Weight:
410.33
Molecular Formula:
C14H15N2NaO9S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker. It is water soluble with a 9.4 angstrom spacer arm. 6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester is widely used in bioconjugation reactions to attach proteins, peptides, or other biomolecules to thiol-containing compounds or surfaces. The maleimide group reacts specifically with free sulfhydryl groups (-SH) present in cysteine residues of proteins, forming a stable thioether linkage.


6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester (CAS 215312-86-0) References

  1. Topology of 1-acyl-sn-glycerol-3-phosphate acyltransferases SLC1 and ALE1 and related membrane-bound O-acyltransferases (MBOATs) of Saccharomyces cerevisiae.  |  Pagac, M., et al. 2011. J Biol Chem. 286: 36438-47. PMID: 21849510
  2. The topology of the ER-resident phospholipid methyltransferase Opi3 of Saccharomyces cerevisiae is consistent with in trans catalysis.  |  Pawlik, G., et al. 2020. J Biol Chem. 295: 2473-2482. PMID: 31932304
  3. DNA-capped Fe 3 O 4/SiO 2 magnetic mesoporous silica nanoparticles for potential controlled drug release and hyperthermia  |  Zhu, Y., & Tao, C. 2015. RSC Advances. 5(29): 22365-22372.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester, 10 mg

sc-217352A
10 mg
$71.00

6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester, 100 mg

sc-217352
100 mg
$367.00