6-AzauridineCan be applied in antiviral studies

6-Azauridine (CAS 54-25-1)

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Application: Can be applied in antiviral studies
CAS Number: 54-25-1
Molecular Weight: 245.19
Molecular Formula: C8H11N3O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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6-Azauridine blocks the conversion of orotic acid into UMP and it is used in antiviral studies.

Physical State :
Solid
Solubility :
Soluble in water.
Storage :
Store at 4° C
Melting Point :
157-159° C (lit.)
Boiling Point :
563.17° C (Predicted)
Density :
~2.1 g/cm3 (Predicted)
Refractive Index :
n20D 1.80 (Predicted)
Optical Activity :
α20/D -133.5º±3.5º, c = 1 in pyridine
IC50 :
Respiratory syncytial virus: EC5050 = 1 µM; Human respiratory syncytial virus: EC5050 = 1.2 µM; Respiratory syncytial virus (RSV) : IC50 = 2.28 µM; Janus kinase 2 mutant JAK2V617F: IC50 = 2.32 µM; Vaccinia virus: EC5050 = 11 µM
Ki Data :
Plasmodium vivax ODCase: Ki= 22.4 µM; Plasmodium falciparum ODCase: Ki= 34.1 µM
pK Values :
pKa: 6.63
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
XY8575000
PubChem CID :
5901
Merck Index :
14: 904
MDL Number :
MFCD00006472
EC Number :
200-199-6
Beilstein Registry :
32281
SMILES :
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1N=CC(=O)NC1=O

Download SDS (MSDS)

Certificate of Analysis

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