5prime-Ethylcarboxamido-2prime,3prime-isopropylidene AdenosineCAS: 39491-53-7
MF: C15H20N6O4
MW: 348.36

5′-Ethylcarboxamido-2′,3′-isopropylidene Adenosine (CAS 39491-53-7)

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CAS Number: 39491-53-7
Molecular Weight: 348.36
Molecular Formula: C15H20N6O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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A template for the development of A2B adenosine receptor agonists. Confirmed to be a full agonist in a functional assay based on the measurement of its capacity to modulate cAMP levels in CHO cells expressing the hA2B receptor.


References

Kemp, B., et al.: Br. J. Pharmacol., 126, 1796 (1999), Peyot, M., et al.: Circ. Res., 86, 76 (2000), Fredholm, B., et al.: Pharmacol. Rev., 53, 527 (2001), Zeng, D., et al.: Drug Dev. Res., 58, 405 (2003), Baraldi, P., et al.: J. Med. Chem., 47, 5535 (2004),

Physical State :
Solid
Solubility :
Soluble in DMSO, Ethanol and Methanol
Storage :
Store at -20° C
Melting Point :
200-202°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
29979735
SMILES :
CCNC(=O)[C@H]1O[C@H](C2OC(C)(C)O[C@@H]12)N1C=NC2=C1N=CN=C2N

Download SDS (MSDS)

Certificate of Analysis

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