Molecular structure of 5-Bromo-2,4-bis(trifluoromethyl)pyridine
5-Bromo-2,4-bis(trifluoromethyl)pyridine
Molecular Weight:
293.99
Molecular Formula:
C7H2BrF6N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hh/Gli Antagonist, GANT58 is a cell-permeable tetrapyridinylthiophene compound that acts as downstream Hedgehog (Hh) pathway blocker and targets Gli-mediated gene transactivation (IC50 ~ 5 7µM in SAG-stimulated Shh-L2 cells). Hh/Gli Antagonist, GANT58 has beem shown to reduce cellular mRNA levels of hedgehog target genes, Gli1, Hip1, Ptch, and inhibit Gli-dependent tumor growth in vitro. Its action appears to be hedgehog pathway-selective, downstream of Smo and Sufu, but does not seem to interfere with Gli DNA binding. Hh/Gli Antagonist, GANT58 is an inhibitor of hedgehog.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Bromo-2,4-bis(trifluoromethyl)pyridine, 500 mg | sc-318352 | 500 mg | $294.00 |