5-(2-Aminoethyl)dithio-2-nitrobenzoic AcidA more base-stable reagent used to quantify thiols

5-(2-Aminoethyl)dithio-2-nitrobenzoic Acid (CAS 71899-86-0)

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Application: A more base-stable reagent used to quantify thiols
CAS Number: 71899-86-0
Molecular Weight: 274.32
Molecular Formula: C9H10N2O4S2
* Refer to Certificate of Analysis for lot specific data (including water content).
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5-(2-Aminoethyl)dithio-2-nitrobenzoic Acid is a more base-stable alternative to Ellman's reagent used to quantify thiol contents and enzymatic assays under basic pH conditions. Experimentally shown to react with free thiols in a similar manner to Ellman's reagent, but with dramatically improved stability.


References

Zhang, H., et al.: Bioorg. Chem., 26, 356 (1998), Chen, Y., et al.: Biochem., 43, 11491 (2004),

Physical State :
Solid
Solubility :
Soluble in Water
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
18363752
SMILES :
C1=CC(=C(C=C1SSCCN)C(=O)O)[N+](=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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