4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt MF: C18H20KNO11S
MW: 497.51

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt is rated 5.0 out of 5 by 1.
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Alternate Names: 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt is also known as MUGS.
Purity: 98%
Molecular Weight: 497.51
Molecular Formula: C18H20KNO11S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt is a fluorogenic substrate for lysosomal N-acetylglucosamine-6-sulphate sulphatase. 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt can be used for prenatal diagnosis of Tay-Sachs disease. 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt may be used for the classification of GM2 gangliosidosis genotypes .


References

1. Greloner, E.E., and Wenger, D.A. 1987. Prenat. Diag. 7, 419.
2. Bayleran, J., et al. 1984. Clin. Chim. Acta143, 73.
3. Inui, K., and Wenger, D.A. 1984. Clin. Genet.25, 93.
4. He, W., et al.: J. inher. Metab. Dis., 16, 935 (1993)

Physical State :
Solid
Solubility :
Soluble in methanol (easily), and water (20 mg/ml).
Storage :
Store at -20° C
Melting Point :
195-197° C
Fluoresence :
λex 360 nm, λem 440 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00797620
SMILES :
CC1=CC(=O)OC2=C1C=CC(=C2)O[[email protected]@H]3[[email protected]]([[email protected]]([[email protected]]([[email protected]@H](O3)CO[S](=O)(=O)[O-])O)O)NC(=O)C.[K+]

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Certificate of Analysis

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I read articles that this substrate from another company (synonym 4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt) is used for Hexosaminidase A activity.Is your product also suitable for Hexosaminidase A enzyme activity?

Asked by: hande
Thanks for your question. Yes, the sc-223640 is a substrate of HEXA and can be used for Hexosaminidase A activity. Please contact Technical service for further support.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06
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Rated 5 out of 5 by from Various publications cite the use of 4 Various publications cite the use of 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy- -D-glucopyranoside Potassium Salt as a fluorogenic substrate of GNS. -SCBT Publication Review
Date published: 2015-02-25
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