Date published: 2025-12-5

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4-Isopropylbenzyl bromide (CAS 73789-86-3)

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CAS Number:
73789-86-3
Molecular Weight:
213.11
Molecular Formula:
C10H13Br
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Isopropylbenzyl bromide is a reactive compound with two benzyl groups, that can be used for chromatography. It may act to inhibit the growth of Cryptococcus neoformans. Functioning as an antibacterial agent, it binds to the ribosomal 50S subunit which inhibits protein synthesis. This compound′s applications are diverse, encompassing the synthesis of polymers and dyes. It has been used for the synthesis of different compounds, spanning thiophenes, indoles, and quinolines.


4-Isopropylbenzyl bromide (CAS 73789-86-3) References

  1. A nucleophilic substitution reaction performed in different types of self-assembly structures.  |  Häger, M., et al. 2004. Langmuir. 20: 6107-15. PMID: 15248691
  2. Synthesis and antifungal activity of a novel series of 13-(4-isopropylbenzyl)berberine derivatives.  |  Park, KD., et al. 2010. Bioorg Med Chem Lett. 20: 6551-4. PMID: 20932752
  3. 9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, is a potent antifungal agent that inhibits the growth of Cryptococcus neoformans by regulating gene expression.  |  Bang, S., et al. 2014. PLoS One. 9: e109863. PMID: 25302492
  4. Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity.  |  Matharu, DS., et al. 2014. J Med Chem. 57: 10314-28. PMID: 25399509
  5. Safranal and its analogs inhibit Escherichia coli ATP synthase and cell growth.  |  Liu, M., et al. 2017. Int J Biol Macromol. 95: 145-152. PMID: 27865956
  6. Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.  |  Mohsin, NU., et al. 2018. Eur J Med Chem. 143: 97-106. PMID: 29172086
  7. Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.  |  Petritsch, M., et al. 2021. Eur J Med Chem. 210: 112969. PMID: 33148495
  8. A novel bis(pyrazolyl)methane compound as a potential agent against Gram-positive bacteria.  |  Seguí, P., et al. 2021. Sci Rep. 11: 16306. PMID: 34381091
  9. A bis(pyrazolyl)methane derivative against clinical Staphylococcus aureus strains isolated from otitis externa.  |  Ocaña, AV., et al. 2022. Laryngoscope Investig Otolaryngol. 7: 283-290. PMID: 35155809
  10. A Dehydrogenative Inverse Electron Demand Diels-Alder Reaction for the Synthesis of Functionalized Pyranones.  |  Sharif, A., et al. 2022. Org Lett. 24: 4316-4321. PMID: 35699407
  11. Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment.  |  Sun, C., et al. 2023. J Med Chem. 66: 2064-2083. PMID: 36579489
  12. Lipase-catalyzed preparation of optically active isomers of cyclamen aldehyde  |  Kawasaki, M., Goto, M., Hu, D., Toyooka, N., & Kometani, T. 2013. Journal of Molecular Catalysis B: Enzymatic. 96: 27-33.
  13. Synthesis of solution-processable poly (3, 4 propylenedioxythiophene) nanobelts for electrochromic device applications  |  Raghavan, S. C., Shivaprakash, N. C., & Sindhu, S. N. 2017. Optical Materials. 73: 56-63.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Isopropylbenzyl bromide, 5 g

sc-232798
5 g
$45.00