4-(Bromomethyl)-6,7-dimethoxycoumarin CAS: 88404-25-5
MF: C12H11BrO4
MW: 299.12
An HPLC fluorescent labeling reagent.

4-(Bromomethyl)-6,7-dimethoxycoumarin (CAS 88404-25-5)

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Application: 4-(Bromomethyl)-6,7-dimethoxycoumarin is an HPLC fluorescent labeling reagent
CAS Number: 88404-25-5
Molecular Weight: 299.12
Molecular Formula: C12H11BrO4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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4-(Bromomethyl)-6,7-dimethoxycoumarin is a reagent for the covalent fluorescent labeling of compounds. 4-(Bromomethyl)-6,7-dimethoxycoumarin is described to react with nucleophilic amino acid residues to introduce the fluorescent tag to protein samples and to react with carboxylic acids for derivatization and determination by HPLC.


References

1. Yu, P.H. and Davis, B.A. 1991. Neuropharmacology. 30: 507-515. PMID: 1865997
2. Stefanova, H.I., et al. 1992. Biochemistry. 31: 6023-6031. PMID: 1385723

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (reacts), dichloromethane, methanol, and chloroform.
Storage :
Store at -20° C
Melting Point :
212-216° C (lit.)
Boiling Point :
417.06° C at 760 mmHg (Predicted)
Density :
1.52 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
Fluoresence :
λex 354 nm, λem 435 nm in methanol; λex 322 nm, λem 395 nm (Reaction product with acetic acid)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
MDL Number :
MFCD00011570
Beilstein Registry :
4750487
SMILES :
COC1=C(C=C2C(=C1)C(=CC(=O)O2)CBr)OC

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Certificate of Analysis

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4-(Bromomethyl)-6,7-dimethoxycoumarin (CAS 88404-25-5)  Product Citations

See how others have used 4-(Bromomethyl)-6,7-dimethoxycoumarin (CAS 88404-25-5). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 11353762  Myers, MJ. et al. 2001. Drug Metab. Dispos. 29: 908-915.

Citations 1 to 1 of 1 total
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