4-(Bromomethyl)-6,7-dimethoxycoumarinAn HPLC fluorescent labeling reagent

4-(Bromomethyl)-6,7-dimethoxycoumarin (CAS 88404-25-5)

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Application: An HPLC fluorescent labeling reagent
CAS Number: 88404-25-5
Molecular Weight: 299.12
Molecular Formula: C12H11BrO4
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* Refer to Certificate of Analysis for lot specific data (including water content).
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4-(Bromomethyl)-6,7-dimethoxycoumarin is a reagent for the covalent fluorescent labeling of compounds. 4-(Bromomethyl)-6,7-dimethoxycoumarin is described to react with nucleophilic amino acid residues to introduce the fluorescent tag to protein samples and to react with carboxylic acids for derivatization and determination by HPLC.


References

1. Yu, P.H. and Davis, B.A. 1991. Neuropharmacology. 30: 507-515. PMID: 1865997
2. Stefanova, H.I., et al. 1992. Biochemistry. 31: 6023-6031. PMID: 1385723

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (reacts), dichloromethane, methanol, and chloroform.
Storage :
Store at -20° C
Melting Point :
212-216° C (lit.)
Boiling Point :
417.06° C at 760 mmHg (Predicted)
Density :
1.52 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
Fluoresence :
λex 354 nm, λem 435 nm in methanol; λex 322 nm, λem 395 nm (Reaction product with acetic acid)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
128870
MDL Number :
MFCD00011570
Beilstein Registry :
4750487
SMILES :
COC1=C(C=C2C(=C1)C(=CC(=O)O2)CBr)OC

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Certificate of Analysis

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4-(Bromomethyl)-6,7-dimethoxycoumarin  Product Citations

See how others have used 4-(Bromomethyl)-6,7-dimethoxycoumarin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 11353762  Myers, MJ. et al. 2001. Drug Metab. Dispos. 29: 908-915.

Citations 1 to 1 of 1 total
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