Date published: 2025-10-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

4-Aminophenylboronic acid (CAS 89415-43-0)

0.0(0)
Write a reviewAsk a question

CAS Number:
89415-43-0
Purity:
98%
Molecular Weight:
136.9
Molecular Formula:
C6H8BNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4-Aminophenylboronic acid, also referred to as 4-APBA, holds significant importance within the realm of medicinal chemistry. This organic compound serves a multitude of purposes in research and laboratory experiments. Its applications encompass drug discovery, drug design, drug delivery, as well as the synthesis of various compounds like peptides, oligonucleotides, and proteins. The scientific research applications of 4-Aminophenylboronic acid are diverse. It finds utility in synthesizing peptides, oligonucleotides, proteins, and drug molecules such as antibiotics, antivirals, and antifungals. Moreover, it plays a role in constructing small-molecule libraries employed for drug screening and discovery. Additionally, 4-Aminophenylboronic acid contributes to the synthesis of fluorescent dyes, facilitating their application in various biomedical imaging techniques. While the complete mechanism of action of 4-Aminophenylboronic acid remains unclear, it is believed to act as a proton acceptor, forming stable complexes with diverse molecules. These complexes, in turn, participate in a range of reactions such as peptide synthesis and drug discovery. Furthermore, 4-Aminophenylboronic acid can function as a catalyst in specific reactions, including the boronic acid-catalyzed reaction involving an amine and a boronic acid.


4-Aminophenylboronic acid (CAS 89415-43-0) References

  1. An ultrasensitive electrochemical immunosensor platform with double signal amplification for indole-3-acetic acid determinations in plant seeds.  |  Yin, H., et al. 2013. Analyst. 138: 1851-7. PMID: 23377501
  2. Sensitive sugar detection using 4-aminophenylboronic acid modified graphene.  |  Wang, Q., et al. 2013. Biosens Bioelectron. 50: 331-7. PMID: 23880108
  3. A fluoride-driven ionic gate based on a 4-aminophenylboronic acid-functionalized asymmetric single nanochannel.  |  Liu, Q., et al. 2014. ACS Nano. 8: 12292-9. PMID: 25482729
  4. High Efficiency of Functional Carbon Nanodots as Entry Inhibitors of Herpes Simplex Virus Type 1.  |  Barras, A., et al. 2016. ACS Appl Mater Interfaces. 8: 9004-13. PMID: 27015417
  5. Structure-Based Design and Synthesis of a New Phenylboronic-Modified Affinity Medium for Metalloprotease Purification.  |  Li, S., et al. 2016. Mar Drugs. 15: PMID: 28036010
  6. Red Emission B, N, S-co-Doped Carbon Dots for Colorimetric and Fluorescent Dual Mode Detection of Fe3+ Ions in Complex Biological Fluids and Living Cells.  |  Liu, Y., et al. 2017. ACS Appl Mater Interfaces. 9: 12663-12672. PMID: 28339185
  7. Functional Carbon Quantum Dots as Medical Countermeasures to Human Coronavirus.  |  Łoczechin, A., et al. 2019. ACS Appl Mater Interfaces. 11: 42964-42974. PMID: 31633330
  8. Nano-crystalline cellulose-coated magnetic nanoparticles for affinity adsorption of glycoproteins.  |  Zhang, J., et al. 2020. Analyst. 145: 3407-3413. PMID: 32253403
  9. Specifically triggered dissociation based ratiometric electrochemical sensor for H2O2 measurement in food samples.  |  Luo, S. and Kan, X. 2022. Food Chem. 387: 132922. PMID: 35421654
  10. Chemotaxis, sporulation, and larvicide production in Bacillus sphaericus 2362. The influence of L-ethionine, and of aminophenylboronic acid.  |  Andreev, J., et al. 1994. FEBS Lett. 347: 231-4. PMID: 8034009
  11. Chemotaxis, sporulation, and larvicide production in Bacillus sphaericus 2362. The influence of L-ethionine, and of aminophenylboronic acid.  |  Andreev, J., et al. 1994. FEBS Lett. 349: 416-9. PMID: 8050606
  12. A new approach for paper-based analytical devices with electrochemical detection based on graphite pencil electrodes  |  M Santhiago, LT Kubota - Sensors and Actuators B: Chemical, 2013 - Elsevier. February 2013,. Sensors and Actuators B: Chemical. Volume 177,: Pages 224-230.
  13. Design of an Automated Electrochemical Biosensor Modified with Phenylboronic Acid to Study Glycoprotein Immobilization  |   and Dr. Zehra Ölçer. October 15, 2020. ChemistrySelect. Volume5, Issue38: Pages 11866-11873.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Aminophenylboronic acid, 1 g

sc-289919
1 g
$464.00

4-Aminophenylboronic acid, 5 g

sc-289919A
5 g
$1841.00