4,5-diphenyl-1,2,3-Thiadiazole CAS: 5393-99-7
MF: C14H10N2S
MW: 238.3
An antibiotic compound with CYP450 inhibitory properties.

4,5-diphenyl-1,2,3-Thiadiazole (CAS 5393-99-7)

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Application: 4,5-diphenyl-1,2,3-Thiadiazole is an antibiotic compound with CYP450 inhibitory properties
CAS Number: 5393-99-7
Molecular Weight: 238.3
Molecular Formula: C14H10N2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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4,5-diphenyl-1,2,3-Thiadiazole has diverse applications in medicine and agriculture, including acting as a bactericide, fungicide, and antiviral agent. It has been shown to selectively inhibit the CYP450 enzymes CYP2B4 and CYP1A2 at concentrations of up to 100 µM, but not CYP2E1.


References

1. Babu, B R., et al., 1997. 1,2,3-Thiadiazole: a novel heterocyclic heme ligand for the design of cytochrome P450 inhibitors. Biochemistry. 36(23): 7209-16. PMID: 9188722

Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
92-94° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1=CC=C(C=C1)C2=C(SN=N2)C3=CC=CC=C3

Download SDS (MSDS)

Certificate of Analysis

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