Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Also found to be effective against Paclitaxel-resistant tumors. Currently in Phase I of clinical testing.
Hoee, G., et al.: Pure Appl. Chem., 71, 11, 2019 (1999), Giannakakou, P., et al.: Proc. Natl. Acad. Sci. USA, 97, 2904 (2000)
Soluble in Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol, Toluene
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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