Date published: 2026-1-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS 762240-92-6)

0.0(0)
Write a reviewAsk a question

CAS Number:
762240-92-6
Molecular Weight:
228.60
Molecular Formula:
C6H8ClF3N4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride is a compound. It is a heterocyclic compound containing a triazolopyrazine ring system, and the trifluoromethyl group is known to enhance the biological activity of similar compounds. 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride is used to study the interactions of small molecules with biological targets, such as receptors or enzymes. Its unique structure and properties make it useful for investigating the mechanisms of action of various biological processes. In biochemical studies, 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride is utilized to explore the structure-activity relationships of potential candidates and The molecular pathways involved in specific physiological functions.


3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS 762240-92-6) References

  1. Highly efficient asymmetric synthesis of sitagliptin.  |  Hansen, KB., et al. 2009. J Am Chem Soc. 131: 8798-804. PMID: 19507853
  2. Liquid chromatographic determination of sitagliptin either alone or in ternary mixture with metformin and sitagliptin degradation product.  |  El-Bagary, RI., et al. 2011. Talanta. 85: 673-80. PMID: 21645757
  3. Design and synthesis of 4-(2,4,5-trifluorophenyl)butane-1,3-diamines as dipeptidyl peptidase IV inhibitors.  |  Zhu, L., et al. 2013. ChemMedChem. 8: 1104-16. PMID: 23671024
  4. Practical Asymmetric Synthesis of Sitagliptin Phosphate Monohydrate.  |  Gao, H., et al. 2018. Molecules. 23: PMID: 29899310
  5. Biological transformation of fexofenadine and sitagliptin by carrier-attached biomass and suspended sludge from a hybrid moving bed biofilm reactor.  |  Henning, N., et al. 2019. Water Res. 167: 115034. PMID: 31581038
  6. Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators.  |  Fang, Y., et al. 2020. Bioorg Chem. 94: 103390. PMID: 31662212
  7. Hunig's base catalyzed synthesis of new 1-(2,3-dihydro-1H-inden-1-yl)-3-aryl urea/thiourea derivatives as potent antioxidants and 2HCK enzyme growth inhibitors.  |  Lachhi Reddy, V., et al. 2020. Bioorg Chem. 95: 103558. PMID: 31911311
  8. Efficient and Straightforward Syntheses of Two United States Pharmacopeia Sitagliptin Impurities: 3-Desamino-2,3-dehydrositagliptin and 3-Desamino-3,4-dehydrositagliptin.  |  Sova, M., et al. 2020. ACS Omega. 5: 5356-5364. PMID: 32201825
  9. Ozonation of Sitagliptin: Removal Kinetics and Elucidation of Oxidative Transformation Products.  |  Hermes, N., et al. 2020. Environ Sci Technol. 54: 10588-10598. PMID: 32867484
  10. Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain.  |  van der Wildt, B., et al. 2021. ACS Chem Neurosci. 12: 4465-4474. PMID: 34757711
  11. Current Threat of Nitrosamines in Pharmaceuticals and Scientific Strategies for Risk Mitigation.  |  Tuesuwan, B. and Vongsutilers, V. 2023. J Pharm Sci. 112: 1192-1209. PMID: 36739905
  12. Identification of new oxospiro chromane quinoline-carboxylate antimalarials that arrest parasite growth at ring stage.  |  Jameel, E., et al. 2023. J Biomol Struct Dyn. 1-22. PMID: 36970842
  13. SAR and lead optimization of (Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(2-morpholinoacetyl)thiazolidine-2,4-dione as a potential multi-target antidiabetic agent.  |  Shah, M., et al. 2023. Eur J Med Chem. 258: 115591. PMID: 37393789

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride, 5 g

sc-209491
5 g
$110.00