Date published: 2025-9-26

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3-Quinolinecarboxylic Acid (CAS 6480-68-8)

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Application:
3-Quinolinecarboxylic Acid is a quinoline derivative with antimicrobial activity
CAS Number:
6480-68-8
Molecular Weight:
173.17
Molecular Formula:
C10H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Quinolinecarboxylic acid, a heterocyclic compound, has garnered significant attention in scientific research due to its diverse range of applications and mechanisms of action. One prominent research area involves its role as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and materials science. Its versatile chemical structure enables functionalization at multiple positions, facilitating the synthesis of structurally diverse molecules with tailored properties and biological activities. Additionally, 3-Quinolinecarboxylic acid has been extensively studied for its biological effects, particularly its interaction with biological macromolecules such as enzymes and receptors. Researchers have explaind its mechanisms of action, including inhibition of key enzymes involved in cellular processes and modulation of signaling pathways implicated in disease pathogenesis. Moreover, this compound has been investigated for its antimicrobial properties, demonstrating inhibitory effects against bacterial and fungal pathogens. Furthermore, its fluorescent properties have been harnessed in biochemical assays and imaging techniques for probing cellular structures and molecular interactions. Ongoing research continues to explore the diverse chemical and biological properties of 3-Quinolinecarboxylic acid, aiming to uncover novel applications in drug discovery, chemical biology, and materials science.


3-Quinolinecarboxylic Acid (CAS 6480-68-8) References

  1. Synthesis and biological evaluation of new 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for treatment of autoimmune disorders: structure-activity relationship.  |  Jönsson, S., et al. 2004. J Med Chem. 47: 2075-88. PMID: 15056005
  2. Cascade synthesis of 3-quinolinecarboxylic ester via benzylation/ propargylation-cyclization.  |  Fan, J., et al. 2008. J Org Chem. 73: 8608-11. PMID: 18834180
  3. Effect of lactic acid producing bacteria on the human intestinal microflora during ampicillin treatment.  |  Black, F., et al. 1991. Scand J Infect Dis. 23: 247-54. PMID: 1906634
  4. Effective antagonists of luteinizing hormone releasing hormone modified at position one.  |  Janecka, A., et al. 1993. Amino Acids. 5: 359-65. PMID: 24190707
  5. Clostridium perfringens toxins (type A, B, C, D, E).  |  McDonel, JL. 1980. Pharmacol Ther. 10: 617-55. PMID: 6255496
  6. Dihydroergot Relatives: Quinolinecarboxamides And Esters  |  Cain, C. K., Plampin, J. N., & SAM, J. 1955. The Journal of Organic Chemistry. 20(4): 466-474.
  7. The Condensation of Grignard Reagents with 3-Pyridyl and 3-Quinolyl Ketones  |  Fuson, R. C., & Miller, J. J. 1957. Journal of the American Chemical Society. 79(13): 3477-3480.
  8. Gold (III) Halide Complexes of 3-and 4-Quinolinecarboxylic Acids  |  Goher, M. A., & Hafez, A. K. 1993. Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry. 23(10): 1753-1765.
  9. The Direct Metalation and Subsequent Functionalization of Trifluoromethyl-Substituted Pyridines and Quinolines  |  Schlosser, M., & Marull, M. 2003. European Journal of Organic Chemistry. 2003(8): 1569-1575.
  10. Synthesis, spectral and photophysical investigation of porphyrazines with eight 3-quinolinecarboxy esters  |  Kiliçarslan, F. A., Erdoğmuş, A., Coşkun, N. Y., Yalçın, S. M., & Gül, A. 2013. Journal of Coordination Chemistry. 66(24): 4316-4329.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Quinolinecarboxylic Acid, 1 g

sc-216547
1 g
$52.00