3-O-MethylsphingomyelinA novel selective inhibitor of neutral sphingomyelinase

3-O-Methylsphingomyelin

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 184ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: A novel selective inhibitor of neutral sphingomyelinase
Purity: 98%
Molecular Weight: 604.85
Molecular Formula: C32H65N2O6P
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

3-O-Methylsphingomyelin is a novel selective inhibitor of N-SMase (neutral sphingomyelinase), (Ki=37 μM) that is cell-permeable and does not inhibit acid sphingomyelinase.


References

1. Lister, M.D., et al. 1995. Biochim. Biophys. Acta 1256: 25-30. PMID: 7742352

Physical State :
Solid
Solubility :
Soluble in ethanol (>25 mg/ml), and DMSO (20 mg/ml) at 50° C.
Storage :
Store at -20° C
Melting Point :
162-166° C
Ki Data :
Brain membrane neutral sphingomyelinase: Ki= 37 µM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
58311991
SMILES :
CCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)([O-])OCC[N+](C)(C)C)NC(=O)CCCCCCC)OC

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 76ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 4ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.