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3-Methylxanthine (CAS 1076-22-8)

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Alternate Names:
2,6-Dihydroxy-3-methylpurine
CAS Number:
1076-22-8
Purity:
≥98%
Molecular Weight:
166.14
Molecular Formula:
C6H6N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Methylxanthine is a compound that has application in the field of biochemistry, particularly as a metabolite related to caffeine and other xanthines in various organisms. Its presence is key in the study of metabolic pathways related to the degradation and synthesis of purine-based compounds. Researchers utilize 3-Methylxanthine in enzymology to investigate the activity and inhibition of xanthine oxidase and other enzymes involved in purine metabolism. This research provides insight into the complex regulatory mechanisms that govern nucleotide turnover in cells. Moreover, as a structural analog of caffeine, 3-Methylxanthine is employed in the study of adenosine receptor binding, allowing for a deeper understanding of signal transduction pathways and cellular response mechanisms. The compound′s utility extends to its role as a standard in chromatographic analyses of xanthine compounds, contributing to the development and refinement of analytical techniques in biochemistry.


3-Methylxanthine (CAS 1076-22-8) References

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  2. Ultrafast dynamics show that the theophylline and 3-methylxanthine aptamers employ a conformational capture mechanism for binding their ligands.  |  Lee, SW., et al. 2010. Biochemistry. 49: 2943-51. PMID: 20214401
  3. Direct conversion of theophylline to 3-methylxanthine by metabolically engineered E. coli.  |  Algharrawi, KH., et al. 2015. Microb Cell Fact. 14: 203. PMID: 26691652
  4. Analysis of Supramolecular Complexes of 3-Methylxanthine with Field Asymmetric Waveform Ion Mobility Spectrometry Combined with Mass Spectrometry.  |  Arthur, KL., et al. 2016. J Am Soc Mass Spectrom. 27: 800-9. PMID: 26914231
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  14. Pharmacokinetics of theophylline and 3-methylxanthine in guinea pigs. I. Single dose administration.  |  Madsen, SM. and Ribel, U. 1981. Acta Pharmacol Toxicol (Copenh). 48: 1-7. PMID: 7223434
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Methylxanthine, 250 mg

sc-206666
250 mg
$84.00

3-Methylxanthine, 1 g

sc-206666A
1 g
$243.00