3-Deazaadenosine is a potent inhibitor of adenosine deaminase, an enzyme that catalyzes the removal of the amine group from adenosine. This compound exhibits antitumor activity against a range of leukemia cell lines. 3-Deazaadenosine is an inhibitor of SAHH.
1. Flexner, C.W., et al. Lancet 339, 438, (1992); 2. Jurgensen, C.H., et al. J. Immunol. 144, 653, (1990)
Store at 4° C
665.69° C at 760 mmHg (Predicted)
1.91 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LeeLee, SY. et al. (PubMed 21311682) reported that induction of the intrinsic apoptotic pathway by 3-Deazaadenosine is mediated by BAX activation in HL-60 cells. -SCBT Publication Review
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